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Comparative Pharmacokinetic Properties of Murine Monoclonal Antibody A7 Modified with Neocarzinostatin, Dextran and Polyethylene Glycol

The murinc monoclonal antibody A7 (Mab A7) was chemically modified with several macromolecnles: dextran, polyethylene glycol and the anti‐cancer polypeptide neocarzinostatin. The pharmacokinetic properties of the combinations were subsequently examined. Radioimmunoassay revealed that all preparation...

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Detalles Bibliográficos
Autores principales: Takashina, Ken‐ichiro, Kitamura, Kazuya, Yamaguchi, Toshiharu, Noguchi, Akinori, Noguchi, Akira, Tsurumi, Hiroshi, Toshio, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1991
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918262/
https://www.ncbi.nlm.nih.gov/pubmed/1720116
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01769.x