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Comparative Pharmacokinetic Properties of Murine Monoclonal Antibody A7 Modified with Neocarzinostatin, Dextran and Polyethylene Glycol
The murinc monoclonal antibody A7 (Mab A7) was chemically modified with several macromolecnles: dextran, polyethylene glycol and the anti‐cancer polypeptide neocarzinostatin. The pharmacokinetic properties of the combinations were subsequently examined. Radioimmunoassay revealed that all preparation...
Autores principales: | Takashina, Ken‐ichiro, Kitamura, Kazuya, Yamaguchi, Toshiharu, Noguchi, Akinori, Noguchi, Akira, Tsurumi, Hiroshi, Toshio, Toshio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1991
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918262/ https://www.ncbi.nlm.nih.gov/pubmed/1720116 http://dx.doi.org/10.1111/j.1349-7006.1991.tb01769.x |
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