Human Tumor–infiltrating Lymphocytes Transfected with Tumor Necrosis Factor Gene Could Augment Cytotoxicity to Autologous Tumor Cells

Human tumor–infiltrating lymphocytes (TILs) derived from pleural or ascitic fluid were incubated with recombinant interleukin 2 and transfected with human tumor necrosis factor (TNF) a gene by the lipofection procedure. The resulting TILs secreted significant amounts of TNF in the culture supernatan...

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Detalles Bibliográficos
Autores principales: Itoh, Yoshinori, Kohgo, Yutaka, Watanabe, Naoki, Kanisawa, Yuji, Sakamaki, Sumio, Takahashi, Minoru, Hirayama, Yasuo, Ono, Hiroyuki, Himeno, Takeshi, Niitsu, Yoshiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1991
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918323/
https://www.ncbi.nlm.nih.gov/pubmed/1752779
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01781.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918323/
https://www.ncbi.nlm.nih.gov/pubmed/1752779
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01781.x

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