Hepatocarcinogenesis in Transgenic Mice Carrying Albumin‐promoted SV40 T Antigen Gene

We have developed transgenic mice that inherit albumin promoter‐regulated simian virus 40 (SV40) large T antigen gene, expressed specifically in hepatocytes. These mice all develop multifocal hepatocellular carcinomas at around 5 months and die of liver insufficiency by 7 months. Sequential morpholo...

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Detalles Bibliográficos
Autores principales: Hino, Okio, Kitagawa, Tomoyuki, Nomura, Kimie, Ohtake, Keiko, Cui, Lixin, Furuta, Yasuhide, Shinichi, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1991
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918330/
https://www.ncbi.nlm.nih.gov/pubmed/1684356
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01785.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918330/
https://www.ncbi.nlm.nih.gov/pubmed/1684356
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01785.x

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