Antitumor Activity and Metabolism of a New Anthracycline‐containing Fluorine (ME2303) in Lewis Lung Carcinoma‐bearing Mice

(7‐O‐(2,6‐Dideoxy‐2‐fluoro‐α‐L‐talopyranosyl)adriamycmone‐14‐hemipimerate (ME2303) showed a more marked growth inhibition of Lewis lung carcinoma than adriamycin (ADM). When administered to s.c. Lewis lung carcinoma‐hearing mice, ME2303 in the plasma and liver was rapidly metabolized and disappeared...

Descripción completa

Detalles Bibliográficos
Autores principales: Tigo, Masaaki, Hoshi, Akio, Kadosawa, Hiroyuki, Fujigaki, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1991
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918335/
https://www.ncbi.nlm.nih.gov/pubmed/1752788
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01798.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918335/
https://www.ncbi.nlm.nih.gov/pubmed/1752788
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01798.x

Ejemplares similares