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Antitumor Activity and Metabolism of a New Anthracycline‐containing Fluorine (ME2303) in Lewis Lung Carcinoma‐bearing Mice
(7‐O‐(2,6‐Dideoxy‐2‐fluoro‐α‐L‐talopyranosyl)adriamycmone‐14‐hemipimerate (ME2303) showed a more marked growth inhibition of Lewis lung carcinoma than adriamycin (ADM). When administered to s.c. Lewis lung carcinoma‐hearing mice, ME2303 in the plasma and liver was rapidly metabolized and disappeared...
Autores principales: | Tigo, Masaaki, Hoshi, Akio, Kadosawa, Hiroyuki, Fujigaki, Masao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1991
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918335/ https://www.ncbi.nlm.nih.gov/pubmed/1752788 http://dx.doi.org/10.1111/j.1349-7006.1991.tb01798.x |
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