Enhancing Potential of 6 Different Carcinogens on Multi‐organ Tumorigenesis after Initial Treatment with N‐Methyl‐N‐nitrosourea in Rats

The advantages of applying a whole‐body concept to the assessment of carcinogenic potential of compounds in a two‐stage model after initiation by N‐methyl‐N‐nitrosourea (MNU) were investigated. Male, 6‐week‐old F344 rats were injected with MNU (20 mg/kg, i. p.) twice a week for 4 weeks and they then...

Descripción completa

Detalles Bibliográficos
Autores principales: Uwagawa, Satoshi, Tsuda, Hiroyuki, Inoue, Tadashi, Tagawa, Yoshiaki, Aoki, Toyohiko, Kagawa, Masataka, Ogiso, Tadashi, Ito, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1991
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918354/
https://www.ncbi.nlm.nih.gov/pubmed/1778764
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01812.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918354/
https://www.ncbi.nlm.nih.gov/pubmed/1778764
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01812.x

Ejemplares similares