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Macrophage–T Cell Interaction Is Essential for the Induction of p75 Interleukin 2 (IL–2) Receptor and IL–2 Responsiveness in Human CD4(+) T Cells

Fresh human CD8(+) T cells showed a strong proliferative response to a high concentration of interleukin 2 (IL–2) in the absence of macrophages. In contrast, CD4(+) T cells revealed no significant IL–2 responsiveness in the absence of macrophages. However, if CD4(+) T cells were cocultured with macr...

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Detalles Bibliográficos
Autores principales: Nakamura, Yoshihiko, Nishimura, Takashi, Tokuda, Yutaka, Kobayashi, Nobumasa, Watanabe, Katsuto, Noto, Takashi, Mitomi, Toshio, Sugamura, Kazuo, Habu, Sonoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1991
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918393/
https://www.ncbi.nlm.nih.gov/pubmed/1902447
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01839.x