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Trial to Induce Prostatic Cancer in ACI/Seg Rats Treated with a Combination of 3,2′‐Dimethyl‐4‐aminobiphenyl and Ethinyl Estradiol

In an attempt to induce prostatic adenocarcinoma at higher incidence in a shorter period, we administered diet containing 0.75 ppm of ethinyl estradiol (EE) for three weeks to ACI/Seg rats, which are predisposed to develop a high incidence of microscopic adenocarcinoma of the prostate at higher age....

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Detalles Bibliográficos
Autores principales: Takai, Kazuhiro, Kakizoe, Tadao, Tanaka, Yoshinori, Tobisu, Ken‐ichi, Aso, Yoshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1991
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918399/
https://www.ncbi.nlm.nih.gov/pubmed/1708755
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01844.x