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Overexpression of c‐Myc Inhibits the Appearance of a Specific DNase I Hypersensitive Site in the β‐Globin Chromatin in Murine Erythroleukemia Cells

To investigate the molecular mechanism of regulation of differentiation by c‐Myc, we examined the acquisition of DNase I hypersensitivity by;β‐globin chromatin in an MEL cell transformant (38–2) in which the c‐myc gene was placed under the control of a metallothionein gene promoter. Of the three DNa...

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Detalles Bibliográficos
Autores principales: Takada, Shinji, Obinata, Masuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1991
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918440/
https://www.ncbi.nlm.nih.gov/pubmed/1904416
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01858.x