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Time‐ and Dose‐dependent Induction of Invasive Urinary Bladder Cancers by N‐Ethyl‐N‐(4‐hydroxybutyl)nitrosamine in B6C3F(1) Mice

A sequential investigation of N‐ethyl‐N‐(4‐hydroxybutyl)nitrosamine (EHBN) bladder carcino‐genesis was performed in male B6C3F(1)mice maintained ad libitum on tap water containing 0.025% EHBN for 4, 12, 20, 28 and 36 weeks. A total of 81 invasive tumors, comprising 55 smiamous cell carcinomas (SCCs)...

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Detalles Bibliográficos
Autores principales: Tamano, Seiko, Hagiwara, Akihiro, Suzuki, Emako, Okada, Masashi, Shirai, Tomoyuki, Fukushima, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1991
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918502/
https://www.ncbi.nlm.nih.gov/pubmed/1906851
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01900.x