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Organ‐specific Modification of Tumor Development by Low‐dose Combinations of Agents in a Rat Wide‐spectrum Carcinogenesis Model

The combined effects of low doses of various carcinogens and carcinogenesis modifiers on tumor development were investigated by using a wide‐spectrum organ carcinogenesis model in F344 rats. These agents were administered as three groups: (1) a group of known hepatocarcinogens; (2) a group of nitros...

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Detalles Bibliográficos
Autores principales: Fukushima, Shoji, Shibata, Masa‐Aki, Hirose, Masao, Kato, Toshio, Tatematsu, Masae, Ito, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1991
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918544/
https://www.ncbi.nlm.nih.gov/pubmed/1908845
http://dx.doi.org/10.1111/j.1349-7006.1991.tb02703.x