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Frequent Loss of Heterozygosity at the MCC Locus on Chromosome 5q21‐22 in Sporadic Colorectal Carcinomas

Recent studies have identified a gene on chromosome 5q, designated MCC (mutated in colorectal cancers), as a candidate for the putative colorectal tumor suppressor gene that is located at 5q21. We examined loss of heterozygosity (LOH) at the MCC locus and its vicinity in sporadic colorectal carcinom...

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Detalles Bibliográficos
Autores principales: Miki, Yoshio, Nishisho, Isamu, Miyoshi, Yasuo, Horii, Akira, Ando, Hiroshi, Nakajima, Toshifusa, Utsunomiya, Joji, Nakamura, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1991
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918609/
https://www.ncbi.nlm.nih.gov/pubmed/1682292
http://dx.doi.org/10.1111/j.1349-7006.1991.tb01935.x