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Insertion/Deletion Polymorphism and Other Restriction Fragment Length Polymorphisms in the MCC Gene

The MCC gene is a candidate as a tumor suppressor gene for colorectal neoplasms. Further, MCC is tightly linked to the familial adenomatous polyposis (FAP) locus by linkage and physical analysis. Hence, restriction fragment length polymorphisms (RFLPs) of this gene might be very useful for presympto...

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Detalles Bibliográficos
Autores principales: Miyoshi, Yasuo, Nishisho, Isamu, Miki, Yoshio, Mori, Takesada, Kinzler, Kenneth W., Vogelstein, Bert, Nakamura, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918660/
https://www.ncbi.nlm.nih.gov/pubmed/1347524
http://dx.doi.org/10.1111/j.1349-7006.1992.tb02344.x