Frequent Occurrence of p53 Gene Mutations in Uterine Cancers at Advanced Clinical Stage and with Aggressive Histological Phenotypes

The clinical and pathological significance of mutation of the p53 tumor‐suppressor gene was examined in 108 cases of primary uterine cancers using single‐strand conformation polymorphism and direct DNA sequencing analyses. Mutation of the p53 gene was detected in 19 (31%) of 62 cases of cancer of th...

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Detalles Bibliográficos
Autores principales: Tsuda, Hitoshi, Hirohashi, Setsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1992
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918705/
https://www.ncbi.nlm.nih.gov/pubmed/1336492
http://dx.doi.org/10.1111/j.1349-7006.1992.tb02743.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918705/
https://www.ncbi.nlm.nih.gov/pubmed/1336492
http://dx.doi.org/10.1111/j.1349-7006.1992.tb02743.x

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