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Lack of Allelic Preference in Amplification and Loss of the c‐myc Oncogene in Methylcholanthrene‐induced Mouse Sarcomas

Sarcomas were induced in Fl mice between C57BL/6N and C3H/He strains by subcutaneous injection of methylcholanthrene. The c‐myc oncogene was found to be amplified in 16 cases among 43 sarcomas of C57BL/6N × C3H/He mice and 1 case among 5 sarcomas of the reciprocal cross. The origin of the amplified...

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Detalles Bibliográficos
Autores principales: Niwa, Ohtsura, Kominami, Ryo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918713/
https://www.ncbi.nlm.nih.gov/pubmed/1483933
http://dx.doi.org/10.1111/j.1349-7006.1992.tb02744.x