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Flow Cytometric Analyses of the Characteristics of Tumor Cells Treated with Two Platinum Compounds: 1,1‐Cyclobutanedicarboxylato(2‐aminomethylpyrrolidine)‐platinum(II) and Cisplatin

In order to reduce the toxicities of cisplatin (DDP) and/or to improve antitumor efficacy, a large number of new platinum analogues have been synthesized. 1,1‐Cyclobutanedicarboxylato(2‐amino‐methylpyrrolidine)platinum(II) (DWA2114R) is one of them. In this study, we characterized the action mechani...

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Detalles Bibliográficos
Autores principales: Inoue, Shoichi, Mizuno, Shigetaka, Ito, Masami, Ohnuma, Takao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918718/
https://www.ncbi.nlm.nih.gov/pubmed/1483936
http://dx.doi.org/10.1111/j.1349-7006.1992.tb02750.x