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Characterization of Acquired Resistance to cis‐Diamminedichloroplatinum(II) in Mouse Leukemia Cell Lines

We have established in vivo cisplatin‐resistant mouse leukemia cell lines, L‐1210/DDP and P388/ DDP, in order to elucidate the mechanism of acquired resistance to cisplatin. Resistance indices were 22 and 14, respectively, when the cells were exposed to cisplatin for 48 h. Uptake of cisplatin by bot...

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Detalles Bibliográficos
Autores principales: Tashiro, Tazuko, Sato, Yuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918780/
https://www.ncbi.nlm.nih.gov/pubmed/1556003
http://dx.doi.org/10.1111/j.1349-7006.1992.tb00089.x