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Somatic Mutation during Metastasis of a Mouse Fibrosarcoma Line Detected by DNA Fingerprint Analysis

Metastatic nodules were examined by DNA fingerprint analysis. The probes used, Pc‐1 and Pc‐2, detect mutations as shifts in bands of the minisatellite loci which are dispersed among chromosomes. Four clonal lines of a fibrosarcoma from an F(1) mouse (C57BL/Ka × C3H/He) were selected for various meta...

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Detalles Bibliográficos
Autores principales: Takada, Toshinori, Suzuki, Satoshi, Sugawara, Yoshiko, Kominami, Ryo, Arakawa, Masaaki, Niwa, Ohtsura, Yokoro, Kenjiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918783/
https://www.ncbi.nlm.nih.gov/pubmed/1555998
http://dx.doi.org/10.1111/j.1349-7006.1992.tb00082.x