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Somatic Mutation during Metastasis of a Mouse Fibrosarcoma Line Detected by DNA Fingerprint Analysis
Metastatic nodules were examined by DNA fingerprint analysis. The probes used, Pc‐1 and Pc‐2, detect mutations as shifts in bands of the minisatellite loci which are dispersed among chromosomes. Four clonal lines of a fibrosarcoma from an F(1) mouse (C57BL/Ka × C3H/He) were selected for various meta...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1992
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918783/ https://www.ncbi.nlm.nih.gov/pubmed/1555998 http://dx.doi.org/10.1111/j.1349-7006.1992.tb00082.x |