Enhanced Tumor Localization of Monoclonal Antibody by Treatment with Kininase II Inhibitor and Angiotensin II

The effect of kininase II inhibitor, enalapril, on the delivery of monoclonal antibody A7 to the targeted tumor was investigated using athymic mice bearing human colon cancer, SVV1116. Enalapril alone, which enhances tumor vascular permeability through the kinin‐generating cascade, did not increase...

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Detalles Bibliográficos
Autores principales: Noguchi, Akinori, Takahashi, Toshio, Yamaguchi, Toshiharu, Kitamura, Kazuya, Noguchi, Akira, Tsurumi, Hiroshi, Takashina, Ken‐ichiroh, Maeda, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1992
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918801/
https://www.ncbi.nlm.nih.gov/pubmed/1582884
http://dx.doi.org/10.1111/j.1349-7006.1992.tb00093.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918801/
https://www.ncbi.nlm.nih.gov/pubmed/1582884
http://dx.doi.org/10.1111/j.1349-7006.1992.tb00093.x

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