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Antitumor Activity and Cellular Accumulation of a New Platinum Complex, (—)‐(R)‐2‐Aminomethylpyrrolidine(1,l‐cyclobutanedicarboxylato)platinum(II) Monohydrate, in Cisplatin‐sensitive and ‐resistant Murine P388 Leukemia Cells

We have examined the cytotoxicity and accumulation of (—)‐(U)‐2‐aminomethylpyrrolidine(1,l‐cyclobutanedicarboxylato)platinum(II) monohydrate (DWA2114R) in parent and cisplatin‐resistant mouse P388 leukemia cells (P388 and P388/DDP), in comparison with those of cisplatin (CDDP) and carboplatin (CBDCA...

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Detalles Bibliográficos
Autores principales: Kamisango, Keiichi, Matsumoto, Tomoko, Akamatsu, Ken‐ichi, Morikawa, Kazumi, Tashiro, Tazuko, Koizumi, Kinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918806/
https://www.ncbi.nlm.nih.gov/pubmed/1582895
http://dx.doi.org/10.1111/j.1349-7006.1992.tb00105.x