Radiosensitization and Hypoxic Cell Toxicity of NLA‐1 and NLA‐2, Two New Bioreductive Compounds

Two new bioreductive compounds, 9‐[3‐(2‐nitro‐l‐imidazolyl)propylamino]acridine hydrochloride (NLA‐1) and 9‐[2‐(2‐nitro‐l‐imidazoryl)ethylamino]acridine hydrochloride (NLA‐2), have been prepared. They feature an acridine ring to intercalate with DNA, a 2‐nitroimidazole ring as the radiosensitizing m...

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Detalles Bibliográficos
Autores principales: Papadopoulou, Maria V., Epperly, Michael W., Shields, Donna S., Bloomer, William D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1992
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918828/
https://www.ncbi.nlm.nih.gov/pubmed/1506276
http://dx.doi.org/10.1111/j.1349-7006.1992.tb00123.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918828/
https://www.ncbi.nlm.nih.gov/pubmed/1506276
http://dx.doi.org/10.1111/j.1349-7006.1992.tb00123.x

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