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A Novel Tetracyclic Peptide, Trapoxin, Induces Phenotypic Change from Transformed to Normal in sis‐Oncogene‐transformed NIH3T3 Cells
A novel tetra cyclic peptide, trapoxin [cyclo(L‐phenylalanyl‐L‐phenylalanyl‐D‐pipecolinyl‐L‐2‐amino‐8‐oxo‐9,10‐epoxy‐decanoyl)], was found to induce the flat phenotype in v‐sis‐transformed NIH3T3 cells at a quite low concentration of 1 ng/ml. Actin stress fiber could be detected after trapoxin treat...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
1992
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918831/ https://www.ncbi.nlm.nih.gov/pubmed/1506265 http://dx.doi.org/10.1111/j.1349-7006.1992.tb00109.x |