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Growth Inhibition by Anchorage‐deficiency Is Associated with Increased Level but Reduced Phosphorylation of Mutant p53

Human breast carcinoma MCF‐7 cells seeded on type I collagen‐coated dishes were provided with an anchor via the collagen receptor, integrin, and grew as actively as those in plastic tissue culture dishes. In contrast, cells seeded on a layer of soft agar became anchorage‐deficient and their growth w...

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Detalles Bibliográficos
Autores principales: Takahashi, Kazuhide, Suzuki, Katsuo, Uehara, Yoshimasa, Ono, Tetsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918832/
https://www.ncbi.nlm.nih.gov/pubmed/1506270
http://dx.doi.org/10.1111/j.1349-7006.1992.tb00115.x