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Growth Inhibition by Anchorage‐deficiency Is Associated with Increased Level but Reduced Phosphorylation of Mutant p53
Human breast carcinoma MCF‐7 cells seeded on type I collagen‐coated dishes were provided with an anchor via the collagen receptor, integrin, and grew as actively as those in plastic tissue culture dishes. In contrast, cells seeded on a layer of soft agar became anchorage‐deficient and their growth w...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1992
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918832/ https://www.ncbi.nlm.nih.gov/pubmed/1506270 http://dx.doi.org/10.1111/j.1349-7006.1992.tb00115.x |