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Cell‐killing Activity and Kinetic Analysis of a Novel Antitumor Compound NC‐190, a Benzo[a]phenazine Derivative

A novel antitumor compound, N‐β‐dimethylaminoethyl 9‐carboxy‐5‐hydroxy‐10‐methoxybenzo[a]‐phenazine‐6‐carboxamide sodium salt (NC‐190), was evaluated for antitumor activity in vitro against cultured tumor cell lines, and the kinetics of cell killing was elucidated. NC‐190 strongly inhibited the grow...

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Detalles Bibliográficos
Autores principales: Nakaike, Shiro, Yamagishi, Takehiro, Nanaumi, Kayoko, Otomo, Susumu, Tsukagoshi, Shigeru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918839/
https://www.ncbi.nlm.nih.gov/pubmed/1506275
http://dx.doi.org/10.1111/j.1349-7006.1992.tb00122.x