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Neonatal Apex Resection Triggers Cardiomyocyte Proliferation, Neovascularization and Functional Recovery Despite Local Fibrosis

So far, opposing outcomes have been reported following neonatal apex resection in mice, questioning the validity of this injury model to investigate regenerative mechanisms. We performed a systematic evaluation, up to 180 days after surgery, of the pathophysiological events activated upon apex resec...

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Detalles Bibliográficos
Autores principales: Sampaio-Pinto, Vasco, Rodrigues, Sílvia C., Laundos, Tiago L., Silva, Elsa D., Vasques-Nóvoa, Francisco, Silva, Ana C., Cerqueira, Rui J., Resende, Tatiana P., Pianca, Nicola, Leite-Moreira, Adelino, D'Uva, Gabriele, Thorsteinsdóttir, Sólveig, Pinto-do-Ó, Perpétua, Nascimento, Diana S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918841/
https://www.ncbi.nlm.nih.gov/pubmed/29503089
http://dx.doi.org/10.1016/j.stemcr.2018.01.042