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Mechanism of Synergistic Cytotoxic Effect between Tumor Necrosis Factor and Hyperthermia

We previously reported that recombinant human tumor necrosis factor (rhTNF) and hyperthermia had a synergistic effect against tumors, in vitro and in vivo. We have now investigated the mechanism of this synergy by measuring the lysosomal enzyme activity and hydroxyl radical production of L‐M cells t...

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Detalles Bibliográficos
Autores principales: Yamauchi, Naofumi, Watanabe, Naoki, Maeda, Masahiro, Okamoto, Tetsuro, Sasaki, Hiroyoshi, Tsuji, Naoki, Tsuji, Yasushi, Umeno, Hiroshi, Akiyama, Shinichiro, Niitsu, Yoshiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918849/
https://www.ncbi.nlm.nih.gov/pubmed/1319987
http://dx.doi.org/10.1111/j.1349-7006.1992.tb01962.x