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(32)P‐Postlabeling Analysis of DNA Adducts in Rats during Estrogen‐induced Hepatocarcinogenesis and Effect of Tamoxifen on DNA Adduct Level

DNA adduct formation in the liver, pancreas, kidneys and uterus in ethynylestradiol (EE)‐induced carcinogenesis and the effect of tamoxifen (TAM) on DNA adduct formation were evaluated in female Wistar JCL rats using the (32)P‐postlabeling method. Hyperplastic nodules were noted in the liver of all...

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Detalles Bibliográficos
Autores principales: Shimomura, Makoto, Higashi, Shunsaku, Mizumoto, Ryuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918853/
https://www.ncbi.nlm.nih.gov/pubmed/1319983
http://dx.doi.org/10.1111/j.1349-7006.1992.tb01947.x