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Reduction of MHC-I expression limits T-lymphocyte-mediated killing of Cancer-initiating cells
BACKGROUND: It has been proposed that cancer establishment, maintenance, and recurrence may be attributed to a unique population of tumor cells termed cancer-initiating cells (CICs) that may include characteristics of putative cancer stem cell-like cells. Studies in lung cancer have shown that such...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918869/ https://www.ncbi.nlm.nih.gov/pubmed/29699516 http://dx.doi.org/10.1186/s12885-018-4389-3 |