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Reduction of MHC-I expression limits T-lymphocyte-mediated killing of Cancer-initiating cells

BACKGROUND: It has been proposed that cancer establishment, maintenance, and recurrence may be attributed to a unique population of tumor cells termed cancer-initiating cells (CICs) that may include characteristics of putative cancer stem cell-like cells. Studies in lung cancer have shown that such...

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Detalles Bibliográficos
Autores principales: Morrison, Brian J., Steel, Jason C., Morris, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918869/
https://www.ncbi.nlm.nih.gov/pubmed/29699516
http://dx.doi.org/10.1186/s12885-018-4389-3