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Porcine pulmonary valve decellularization with NaOH-based vs detergent process: preliminary in vitro and in vivo assessments

BACKGROUND: Glutaraldehyde fixed xenogeneic heart valve prosthesis are hindered by calcification and lack of growth potential. The aim of tissue decellularization is to remove tissue antigenicity, avoiding the use of glutaraldehyde and improve valve integration with low inflammation and host cell re...

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Detalles Bibliográficos
Autores principales: van Steenberghe, Mathieu, Schubert, Thomas, Gerelli, Sébastien, Bouzin, Caroline, Guiot, Yves, Xhema, Daela, Bollen, Xavier, Abdelhamid, Karim, Gianello, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918872/
https://www.ncbi.nlm.nih.gov/pubmed/29695259
http://dx.doi.org/10.1186/s13019-018-0720-y