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Enhancing Effect of Pokeweed Mitogen on the Proliferation and the Cytotoxicity of Lymphokine‐activated Killer Cells

In order to obtain more potent lymphokine‐activated killer (LAK) cells for use in adoptive immunotherapy, pokeweed mitogen (PWM) was added to the culture medium for the initial 24–48 h of culturing. The proliferation rate of PWM‐stimulated LAK cells reached about 1000‐fold after 3‐week culture. This...

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Detalles Bibliográficos
Autores principales: Kimoto, Yasuhiko, Tanaka, Toshishige, Fujiwara, Akira, Fujita, Masahide, Taguchi, Tetsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918890/
https://www.ncbi.nlm.nih.gov/pubmed/1379578
http://dx.doi.org/10.1111/j.1349-7006.1992.tb00136.x