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Complex evolution of the GSTM gene family involves sharing of GSTM1 deletion polymorphism in humans and chimpanzees

BACKGROUND: The common deletion of the glutathione S-transferase Mu 1 (GSTM1) gene in humans has been shown to be involved in xenobiotic metabolism and associated with bladder cancer. However, the evolution of this deletion has not been investigated. RESULTS: In this study, we conducted comparative...

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Detalles Bibliográficos
Autores principales: Saitou, M., Satta, Y., Gokcumen, O., Ishida, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918908/
https://www.ncbi.nlm.nih.gov/pubmed/29695243
http://dx.doi.org/10.1186/s12864-018-4676-z