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Androgen Receptor Is Inactivated and Degraded in Bladder Cancer Cells by Phenyl Glucosamine via miR-449a Restoration

BACKGROUND: Bladder cancer caused by exposure to aniline dyes, chronic cystitis, and smoking is detected in approximately 70 000 new cases annually. In the USA alone, it leads to 15 000 deaths every year. In the present study, we investigated the role of 3-((4′-amino-[1,1′-biphenyl]-4-yl)amino)-4-br...

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Detalles Bibliográficos
Autores principales: Guo, Ju, Hu, Jieping, Cao, Runfu, Chen, Qingsheng, Li, Kanghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918918/
https://www.ncbi.nlm.nih.gov/pubmed/29659560
http://dx.doi.org/10.12659/MSM.906836