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Dose Dependence of N‐Hydroxy‐3,2′‐dimethyM‐aminobiphenyl‐induced Rat Prostate Carcinogenesis

Groups of F344 rats were administered biweekly intraperitoneal injections of N‐hydroxy‐3,2′‐dimethyl‐4‐aminobiphenyl (N‐OH‐DMAB) at a dose of 5, 10 or 20 mg/kg body weight or DMAB, the parent compound, at a dose of 25 mg/kg body weight, for a total of 10 times. Prostate carcinomas in the ventral lob...

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Detalles Bibliográficos
Autores principales: Shirai, Tomoyuki, Iwasaki, Shogo, Naito, Hatsumi, Masui, Tsuneo, Kato, Toshio, Imaida, Katsumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918925/
https://www.ncbi.nlm.nih.gov/pubmed/1517147
http://dx.doi.org/10.1111/j.1349-7006.1992.tb01968.x