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Therapeutic Effect of Ansamitocin Targeted to Tumor by a Bispecific Monoclonal Antibody

We have constructed a murine hybrid hybridoma that secretes a bispecific monoclonal antibody (mAb) by fusing a hybridoma secreting an anti‐ansamitocins mAb with a hybridoma secreting an anti‐human transferrin receptor (TfR) mAb that binds to human A431 epidermoid carcinoma cells. The bispecific mAb,...

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Detalles Bibliográficos
Autores principales: Okamoto, Kayoko, Harada, Kaori, Ikeyama, Shuichi, Iwasa, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918935/
https://www.ncbi.nlm.nih.gov/pubmed/1517150
http://dx.doi.org/10.1111/j.1349-7006.1992.tb01977.x