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High Susceptibility to Lung Cancer Analyzed in Terms of Combined Genotypes of P450IA1 and Mu‐class Glutathione S‐Transferase Genes
Lung cancer is closely associated with cigarette smoking. Aromatic hydrocarbons in smoke, including benzo[n]pyrene, first require metabolic activation by Phase I enzymes, cytochrome P450, to their ultimate forms, and these activated forms are then subjected to detoxification by Phase II enzymes, esp...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Blackwell Publishing Ltd
1992
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918950/ https://www.ncbi.nlm.nih.gov/pubmed/1399823 http://dx.doi.org/10.1111/j.1349-7006.1992.tb01992.x |