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Enhancing Effects of Harman and Norharman on Induction of Preneoplastic and Neoplastic Kidney Lesions in Rats Initiated with N‐Ethyl‐N‐hydroxyethylnitrosamine

The modifying potential of two nephrotoxic agents, harman and norharman, on N‐ethyl‐N‐hydroxyethylnitrosamine (EHEN)‐induced renal and hepatic carcinogenesis was investigated in male F344/DuCrj rats. Animals were given 0.1% EHEN in their drinking water for the first 2 weeks as an initiator. Subseque...

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Detalles Bibliográficos
Autores principales: Hagiwara, Akihiro, Sano, Masashi, Asakawa, Emiko, Tanaka, Hikaru, Hasegawa, Ryohei, Ito, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918970/
https://www.ncbi.nlm.nih.gov/pubmed/1429205
http://dx.doi.org/10.1111/j.1349-7006.1992.tb02006.x