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Proline oxidase controls proline, glutamate, and glutamine cellular concentrations in a U87 glioblastoma cell line
L-Proline is a multifunctional amino acid that plays an essential role in primary metabolism and physiological functions. Proline is oxidized to glutamate in the mitochondria and the FAD-containing enzyme proline oxidase (PO) catalyzes the first step in L-proline degradation pathway. Alterations in...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918996/ https://www.ncbi.nlm.nih.gov/pubmed/29694413 http://dx.doi.org/10.1371/journal.pone.0196283 |