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One-carbon metabolism biomarkers and genetic variants in relation to colorectal cancer risk by KRAS and BRAF mutation status

Disturbances in one-carbon metabolism, intracellular reactions involved in nucleotide synthesis and methylation, likely increase the risk of colorectal cancer (CRC). However, results have been inconsistent. To explore whether this inconsistency could be explained by intertumoral heterogeneity, we ev...

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Detalles Bibliográficos
Autores principales: Myte, Robin, Gylling, Björn, Häggström, Jenny, Schneede, Jörn, Löfgren-Burström, Anna, Huyghe, Jeroen R., Hallmans, Göran, Meyer, Klaus, Johansson, Ingegerd, Ueland, Per Magne, Palmqvist, Richard, Van Guelpen, Bethany
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919009/
https://www.ncbi.nlm.nih.gov/pubmed/29694444
http://dx.doi.org/10.1371/journal.pone.0196233