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Analysis of DNA Fragmentation in Human Uterine Cervix Carcinoma HeLa S(3) Cells Treated with Duocarmycins or Other Antitumor Agents by Pulse Field Gel Electrophoresis

Pulse field gel electrophoresis using a contour‐clamped homogeneous electric field was applied for the analysis of DNA‐fragmenting activity of antitumor agents towards human uterine cervix carcinoma HeLa S(3) cells. Duocarmycins (DUMs), novel antitumor antibiotics with ultrapotent cell growth‐inhibi...

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Detalles Bibliográficos
Autores principales: Okamoto, Akihiko, Okabe, Masami, Gomi, Katsushige
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919028/
https://www.ncbi.nlm.nih.gov/pubmed/8449832
http://dx.doi.org/10.1111/j.1349-7006.1993.tb02789.x