Primary Gastric Carcinoma Cells Frequently Lose Heterozygosity at the APC and MCC Genetic Loci

Loss of heterozygosity (LOH) at APC and MCC gene loci (both mapped to 5q21) was investigated in 24 surgical specimens of primary gastric carcinomas using the polymerase chain reaction after tumor cell enrichment by cell sorting based on differences in DNA content. LOH at APC and/or MCC was detected...

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Detalles Bibliográficos
Autores principales: Tamura, Gen, Maesawa, Chihaya, Suzuki, Yasushi, Ogasawara, Satoshi, Terashima, Masanori, Saito, Kazuyoshi, Satodate, Ryoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1993
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919060/
https://www.ncbi.nlm.nih.gov/pubmed/8226275
http://dx.doi.org/10.1111/j.1349-7006.1993.tb02794.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919060/
https://www.ncbi.nlm.nih.gov/pubmed/8226275
http://dx.doi.org/10.1111/j.1349-7006.1993.tb02794.x

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