Oligomeric interfaces as a tool in drug discovery: Specific interference with activity of malate dehydrogenase of Plasmodium falciparum in vitro

Malaria remains a major threat to human health, as strains resistant to current therapeutics are discovered. Efforts in finding new drug targets are hampered by the lack of sufficiently specific tools to provide target validation prior to initiating expensive drug discovery projects. Thus, new appro...

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Detalles Bibliográficos
Autores principales: Lunev, Sergey, Butzloff, Sabine, Romero, Atilio R., Linzke, Marleen, Batista, Fernando A., Meissner, Kamila A., Müller, Ingrid B., Adawy, Alaa, Wrenger, Carsten, Groves, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919072/
https://www.ncbi.nlm.nih.gov/pubmed/29694407
http://dx.doi.org/10.1371/journal.pone.0195011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919072/
https://www.ncbi.nlm.nih.gov/pubmed/29694407
http://dx.doi.org/10.1371/journal.pone.0195011

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