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Chemical Modification by Polyethylene Glycol of the Anti‐tumor Enzyme Arginine Deiminase from Mycoplasma arginini

Ammo acid‐degrading enzymes are known to inhibit the growth of tumor cells in culture by depleting amino acids in the medium. Here we demonstrate that arginine deiminase (EC 3.5.3.6) from Mycoplasma arginini had stronger growth‐inhibitory activity against all 4 kinds of tumor cell lines tested than...

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Detalles Bibliográficos
Autores principales: Takaku, Haruo, Misawa, Satoru, Hayashi, Hideya, Miyazaki, Kaoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919086/
https://www.ncbi.nlm.nih.gov/pubmed/8276724
http://dx.doi.org/10.1111/j.1349-7006.1993.tb02821.x