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Suppression of Anti‐tumor CD4(+) T Cell Responsiveness in the Tumor‐bearing State and Its Recovery in in vitro Culture Free of Tumor Burden

We investigated whether the responsiveness of anti‐tumor CD4(+) T cells suppressed in the tumor‐bearing state is reversed in conditions free of tumor burden. Spleen cells from BALB/c mice bearing a syngeneic tumor (CSA1M) 1–3 wk after inoculation with CSA1M cells produced interleukin‐2 (IL‐2) and IL...

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Detalles Bibliográficos
Autores principales: Nagata, Takako, Zou, Jian‐Ping, Yamamoto, Norihiko, Ono, Shiro, Fujiwara, Hiromi, Hamaoka, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919096/
https://www.ncbi.nlm.nih.gov/pubmed/7903964
http://dx.doi.org/10.1111/j.1349-7006.1993.tb02819.x