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Intracellular Metabolism and Cytotoxicity of Transferrin‐Neocarzinostatin Conjugates of Differing Molar Ratios

Transferrin‐neocarzinostatin (NCS) conjugates with differing molar ratios of drug to protein were synthesized and their intracellular metabolism was investigated. The conjugate mixtures of transferrin‐NCS were separated by DEAE‐Sephacel column chromatography. The separated molecular species were exa...

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Detalles Bibliográficos
Autores principales: Sasaki, Katsunori, Kohgo, Yutaka, Kato, Junji, Kondo, Hitoshi, Niitsu, Yoshiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919126/
https://www.ncbi.nlm.nih.gov/pubmed/8463135
http://dx.doi.org/10.1111/j.1349-7006.1993.tb02854.x