Detection of PML/Retinoic Acid Receptor α Gene Rearrangements by Polymerase Chain Reaction Using Genomic DNA in Patients with Acute Promyelocytic Leukemia

Breakpoints of the 15;17 translocation in patients with acute promyelocytic leukemia (APL) have been identified within PML and retinoic acid receptor α (RARA) genes in chromosomes 15 and 17, respectively. A wide heterogeneity was observed in the breakpoints on the PML and RARA genes. Therefore, ampl...

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Detalles Bibliográficos
Autores principales: Tashiro, Satoshi, Tanaka, Kimio, Asou, Hiroya, Kyo, Taiichi, Dohy, Hiroo, Suzuki, Katsuyuki, Kamada, Nanao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1993
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919129/
https://www.ncbi.nlm.nih.gov/pubmed/8385082
http://dx.doi.org/10.1111/j.1349-7006.1993.tb02841.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919129/
https://www.ncbi.nlm.nih.gov/pubmed/8385082
http://dx.doi.org/10.1111/j.1349-7006.1993.tb02841.x

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