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Detection of PML/Retinoic Acid Receptor α Gene Rearrangements by Polymerase Chain Reaction Using Genomic DNA in Patients with Acute Promyelocytic Leukemia
Breakpoints of the 15;17 translocation in patients with acute promyelocytic leukemia (APL) have been identified within PML and retinoic acid receptor α (RARA) genes in chromosomes 15 and 17, respectively. A wide heterogeneity was observed in the breakpoints on the PML and RARA genes. Therefore, ampl...
Autores principales: | Tashiro, Satoshi, Tanaka, Kimio, Asou, Hiroya, Kyo, Taiichi, Dohy, Hiroo, Suzuki, Katsuyuki, Kamada, Nanao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1993
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919129/ https://www.ncbi.nlm.nih.gov/pubmed/8385082 http://dx.doi.org/10.1111/j.1349-7006.1993.tb02841.x |
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