Cargando…

Comparative Studies on the Metabolism of New Fluorinated Pyrimidine Drugs in the Liver by in vivo(19)F Magnetic Resonance Spectroscopic Observation

1‐Ethoxymethyl‐5‐fluorouracil (EM‐FU) is a fluorinated pyrimidine derived from 5‐FU, and 3‐cyano‐2,6‐dihydroxypyridine (CNDP) is a chemical modulator which suppresses the catabolism of 5‐FU by inhibiting dihydrouracil dehydrogenase in the liver. In this study, the metabolism of EM‐FU and the suppres...

Descripción completa

Detalles Bibliográficos
Autores principales: Harada, Masafumi, Nishitani, Hiromu, Koga, Keiko, Miura, Iwao, Kimura, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919136/
https://www.ncbi.nlm.nih.gov/pubmed/8463136
http://dx.doi.org/10.1111/j.1349-7006.1993.tb02855.x