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Comparative Studies on the Metabolism of New Fluorinated Pyrimidine Drugs in the Liver by in vivo(19)F Magnetic Resonance Spectroscopic Observation

1‐Ethoxymethyl‐5‐fluorouracil (EM‐FU) is a fluorinated pyrimidine derived from 5‐FU, and 3‐cyano‐2,6‐dihydroxypyridine (CNDP) is a chemical modulator which suppresses the catabolism of 5‐FU by inhibiting dihydrouracil dehydrogenase in the liver. In this study, the metabolism of EM‐FU and the suppres...

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Detalles Bibliográficos
Autores principales:	Harada, Masafumi, Nishitani, Hiromu, Koga, Keiko, Miura, Iwao, Kimura, Akio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1993
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919136/ https://www.ncbi.nlm.nih.gov/pubmed/8463136 http://dx.doi.org/10.1111/j.1349-7006.1993.tb02855.x

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