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Induction of BCR‐ABL Fusion Genes by in vitro X‐irradiation

The Philadelphia chromosome consists of a reciprocal translocation between the ABL oncogene at chromosome 9q34 and the BCR gene at chromosome 22q1l, resulting in the expression of chimeric BCR‐ABL mRNAs specific to chronic myelogenous leukemia (CML). Presence of the fusion gene can be detected with...

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Detalles Bibliográficos
Autores principales: Ito, Takashi, Seyama, Toshio, Mizuno, Terumi, Hayashi, Tomonori, Iwamoto, Keisuke S., Dohi, Kiyohiko, Nakamura, Nori, Akiyama, Mitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1993
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919137/
https://www.ncbi.nlm.nih.gov/pubmed/8463127
http://dx.doi.org/10.1111/j.1349-7006.1993.tb02840.x